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BMB PhD Program Faculty

Kenneth Kinzler

Cancer genetics to improve detection & treatment

Professor

Department of Oncology
School of Medicine

Kenneth Kinzler

Research Overview

Cancer is a leading cause of death and morbidity in the United States and this problem is expected to grow as our life expectancy increases. Our laboratory has focused on the genetics of human cancer with a particular emphasis on exploring how inherited and somatic mutations can improve the clinical management of cancer. We have identified over a dozen cancer driver genes and the hereditary basis of several cancer predisposition syndromes. We have also developed several novel technologies to facilitate our studies of cancer. In particular we have focused on the development of digital genomic methods for detecting trace levels of tumor DNA. Most recently, we have focused on applying the above advances to the early detection of cancer and cancer immunotherapy. 

Additional Titles

Director, Ludwig Center at Johns Hopkins University

 

 

Topic Areas

Selected Publications