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Executive Director of the Biostatistics Center
Senior Scientist
Gayane Yenokyan

Departmental Affiliations


Center & Institute Affiliations

Gayane Yenokyan, MD, PhD '09, MHS '09, MPH, is a consulting statistician leading the Biostatistics Center and co-directing the JH ICTR Biostatistics Program.

Contact Info

Research Interests

Statistical consulting; Covariate-adaptive randomization; patient-reported outcomes; recovery post hemorrhagic stroke; Familial Mediterranean fever (FMF)
Experiences & Accomplishments
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins School of Arts and Sciences
American University of Armenia
Yerevan State Medical University
Trained as an epidemiologist and biostatistician, I have been practicing statistical consulting for more than 15 years. During this time, I have collaborated with numerous investigators and provided statistical support for grants, abstract- and manuscript preparation and scientific report writing. My early collaborations included time-to-event analyses of obstructive sleep apnea (OSA) and other sleep-disordered breathing as risk factors for the development of cardiovascular disease as well as evaluation of longitudinal outcome trajectories in children and adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD), bipolar disorder, mood dysregulation, and concussion. More recently I have joined the JHU-Tufts Trial Innovation Center (TIC) as the lead biostatistician providing trial design and execution leadership for supporting NIH/NCATS-funded Helping to End Addiction Long-Term (HEAL) Pain Management Effectiveness Research Network (ERN) program. I have served as a primary biostatistician in clinical trials testing the role of a behavioral intervention to promote better end-of-life decisions, psychotherapy for mood and behavior dysregulation, nurse education program for prevention of thromboembolism, prevention of central-line-associated bloodstream infections as well as treatment of hemorrhagic stroke and post stroke recovery.
Since 2011, I teach the "Introduction to Clinical Research" course offered through the Institute for Clinical and Translational Research (ICTR) to provide formal clinical research training a group of prospective investigators in wide range of clinical fields. I am also one of the principal faculty in the Graduate Training Program in Clinical Investigation, a joint venture between the Johns Hopkins Bloomberg School of Public Health and School of Medicine; it trains clinical faculty, postdoctoral fellows and other health professionals to be more effective clinical scientists by giving them skills in necessary to design and conduct clinical investigations of emerging medical treatments and technologies. I teach both in-class and on-line versions of the Quantitative Analysis of Clinical Data course.
Honors & Awards
2019-“Contribution of the Year” award for “Identifying predictive behavioral markers: A demonstration using automatically reinforced self-injurious behavior”. Journal of Applied Behavior Analysis. 2018. Jul;51(3):443-465
2013 -American Academy of Child and Adolescent Psychiatry’s Elaine Schlosser Lewis Award for Best Paper on ADHD published in Journal of the American Academy of Child and Adolescent Psychiatry for “The Preschool Attention-Deficit/Hyperactivity Disorder Treatment Study (PATS) 6-year follow-up”. JAACAP, 2013; 52(3):264-278.
2011 - Circulation’s "Best Paper Award" in the category of Population Science for "Prospective Study of Obstructive Sleep Apnea and Incident Coronary Heart Disease and Heart Failure: The Sleep Heart Health Study”. Circulation, 2010; 122: 352-360 by Gottlieb DJ, Yenokyan G, Newman AB, O’Connor GT, Punjabi NM, Quan SF.
2001- Global Supplementary Grant, Open Society Institute (OSI) 2001 - Edmund S. Muskie Freedom Support Act Graduate Fellowship, US Department of State
Select Publications
These are my most recent publications
  • Ehsani JP, Weast R, Chirles T, Hellinger A, Shields W, Yenokyan G, Igusa T Evaluating a smartphone application to increase the quantity and improve the quality of supervised practice driving. Inj Prev. 2021 Aug19:injuryprev-2021-044247. doi: 10.1136/injuryprev-2021-044247.
  • Milstone AM, Rosenberg C, Yenokyan G, Koontz DW, Miller MR; CCLIP AuthorshipGroup. Alcohol-impregnated caps and ambulatory central-line-associated bloodstream infections (CLABSIs): A randomized clinical trial. Infect ControlHosp Epidemiol. 2020 Oct 12:1-9. doi: 10.1017/ice.2020.467.
  • Hanley DF, Thompson RE, Rosenblum M, Yenokyan G, Lane K, McBee N, …Ziai W, Zuccarello M,Awad IA; MISTIE III Investigators. Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial. Lancet.2019 Mar 9;393(10175):1021-1032. doi: 10.1016/S0140-6736(19)30195-3.
  • Haut ER, Aboagye JK, Shaffer DL, Wang J, Hobson DB, Yenokyan G, Sugar EA,Kraus PS, Farrow NE, Canner JK, Owodunni OP, Florecki KL, Webster KLW ,Holzmueller CG, Pronovost PJ, Streiff MB, Lau BD. Effect of Real-time Patient-Centered Education Bundle on Administration of Venous Thromboembolism Prevention in Hospitalized Patients. JAMA Netw Open. 2018 Nov 2;1(7):e184741. doi:10.1001/jamanetworkopen.2018.4741.
  • Hagopian LP, Rooker GW, Yenokyan G. Identifying predictive behavioral markers: A demonstration using automatically reinforced self-injurious behavior. J Appl Behav Anal. 2018 Jul;51(3):443-465. doi: 10.1002/jaba.477. Epub 2018 May21. PMID: 29781180; PMCID: PMC7269171.
A Necessary Shift: Determining the Capacity of and Guidelines for Virtual Youth Mentoring