Johns Hopkins Bloomberg School of Public Health
2025-04-21 16:052025-04-21 17:20UTCuse-titleLocation
Wolfe Street Building/W3030
Biostatistics Department Seminar
Title: Leveraging Bayesian mixture models to identify high-dimensional exposure patterns in heterogeneous populations
Abstract: Mixture models have found great utility to uncover patterns in large, heterogeneous study populations. However, majority subgroups within that population can, at times, overpower the direction and characterization of these patterns, leaving information of smaller-sized subgroups overlooked and ignored. This is commonly seen in a population such as the United States (US) where different backgrounds and subpopulations coexist. Unfortunately, much of the research which motivates US policy and decision making is driven by data accommodating the majority subgroup in the population. This ‘one-size-fits-all’ approach can be problematic if interventions and policy decisions are based on study results that are not representative of the entire population it intends to serve. This talk will discuss how we can leverage extensions of the standard mixture model framework to uncover exposure patterns from high-dimensional data within and across subpopulations that are typically overshadowed in population-based research.
Speaker
Briana Stephenson is an assistant professor of Biostatistics at the Harvard T.H. Chan School of Public Health
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2024-2025 Monday Seminar Series
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