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Renan Castillo, PhD '08, MS, leads a consortium that conducts clinical trials and observational cohorts to study trauma, orthopedics, and disability.

Contact Info

624 N. Broadway, Hampton House 543

Research Interests

Trauma Outcomes, Pain, Structural Equation Modeling, Disparities, Cognitive Behavioral Therapy, Self Management Interventions

Experiences & Accomplishments
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins University
Johns Hopkins University

Trauma Outcomes. Orthopedic Trauma. Clinical Trials, Pain and Psychologic Distress. Structural Models. Health Disparities. Cognitive Behavioral Therapy. Self Management Interventions.

Honors & Awards

2004 Orthopedic Trauma Association Annual Meeting: Paper selected for presentation at Specialty Day at the American Academy of Orthopedic Surgeons

American Academy of Orthopedic Surgeons 2003 Ann Doner Vaugham Kappa Delta Award for Best Research Project (as part of the LEAP research team).

2003 Orthopedic Trauma Association Annual Meeting: Paper selected for presentation at Specialty Day at the American Academy of Orthopedic Surgeons.


Select Publications

    Castillo RC, Wegener ST, Heins SE, Haythornthwaite JA, Mackenzie EJ, Bosse MJ; the LEAP Study Group. Longitudinal relationships between anxiety, depression, and pain: Results from a two-year cohort study of lower extremity trauma patients. Pain, 154(12):2860-6, Aug 29 2013.



    Castillo RC, Wegener ST, Newell MZ, Carlini AR, Bradford AN, Heins SE, Pollak AN, Teter H, MacKenzie EJ. Improving outcomes at Level I trauma centers: an early evaluation of the Trauma Survivors Network. Journal of Trauma and Acute Care Surgery; 74(6):1534-40, Jun 2013.



    Castillo RC, MacKenzie EJ, Bosse MJ. Measurement of Functional Outcomes in the Major Extremity Trauma Research Consortium (METRC). Journal of the American Academy of Orthopaedic Surgery. 2012;20 Suppl 1:S59-63. doi: 10.5435/JAAOS-20-08-S59.



    Castillo RC, Scharfstein DO, MacKenzie EJ. Observational studies in the era of Randomized Trials: Finding the Balance.  Journal of Bone and Joint Surgery. 2012 Jul 18;94 Suppl 1:112-7.



    Castillo RC, Bosse MJ, MacKenzie EJ, and the LEAP study group. “Orthopaedic Trauma Clinical Research: Is Two Year Follow-up Necessary? Results from a Longitudinal Study of Severe Lower Extremity Trauma.” Journal of Orthopaedic Trauma. 2011 Dec;71(6):1726-31.


Validation of PROMIS for Orthopaedic Trauma Research
Improving Trauma Outcomes: A Patient-Centered Approach
Assessing Barriers to Implementation of the Trauma Survivors Network
Supplemental Perioperative Oxygen to Reduce Surgical Site Infection in At-Risk Fracture Surgery
Treatment of Early Post-Op Wound Infection after Plate Internal Fixation
Novel Therapy to Reduce Infection after Operative Treatment of Fractures at High Risk of Infection: A Multicenter Randomized Controlled Trial
Development of a Screening Tool for Delayed Return to Work Following Low Back Injuries
Qualitative Assessment of the Benefits of Peer Visitation
Reliability and Responsiveness of PROMIS tools in Orthopaedic Trauma Patients
The Major Extremity Trauma and Rehabilitation Consortium