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Genevieve
Wojcik
,
PhD

Associate Professor
Genevieve Wojcik

Departmental Affiliations

Primary
Division
Genetic Epidemiology

Contact Info

615 N. Wolfe Street, Room W6515
Baltimore
Maryland
21205
US        

Research Interests

Genetic Epidemiology; Diverse Populations; Infectious Diseases; Host-Pathogen Dynamics; Polygenic Risk Scores; Population Genetics
Experiences & Accomplishments
Education
PhD
Johns Hopkins Bloomberg School of Public Health
2013
MHS
Johns Hopkins Bloomberg School of Public Health
2010
BA
Cornell University
2008
Overview
I am an Assistant Professor of Epidemiology at the Johns Hopkins Bloomberg School of Public Health in Baltimore, Maryland. As a statistical geneticist and genetic epidemiologist, my research focuses on method development for diverse populations, specifically in admixed populations. As the majority of genomic research is conducted in populations of European descent, many of the tools and frameworks utilized are optimized for homogeneous populations. However, the largest minority groups within the United States are admixed, drawing recent genetic ancestry from two or more continental populations. Many of my efforts focus on improving statistical methods for complex trait mapping and polygenic risk scores for these populations to address existing health inequities and ensure downstream translation for all.

The second arm of my research program focuses on the genetic susceptibility to infectious disease and vaccine response, with an eye towards host-pathogen co-evolution. This is a natural complement to my work in diverse populations as the burden of infectious disease morbidity and mortality is predominantly in non-European populations.

I am currently a member of numerous NIH consortia, including the Population Architecture using Genomics and Epidemiology (PAGE) Study, the Genome Sequencing Program (GSP), the Clinical Genome Resource (ClinGen), and the Environmental influences on Child Health Outcomes (ECHO) program, as well as several international collaborations.
Select Publications
Select publications from the last few years.
  • Wojcik GL et al. Genetic analyses of diverse populations improves discovery for complex traits. Nature. 2019 Jun;570(7762):514-518. doi: 10.1038/s41586-019-1310-4. Epub 2019 Jun 19. PubMed PMID: 31217584.
  • Wojcik GL et al. Imputation-Aware Tag SNP Selection To Improve Power for Large-Scale, Multi-ethnic Association Studies. G3 (Bethesda). 2018 Oct 3;8(10):3255-3267. doi: 10.1534/g3.118.200502. PubMed PMID: 30131328; PubMed Central PMCID: PMC6169386.
  • Wojcik GL et al. Genome-Wide Association Study Reveals Genetic Link between Diarrhea-Associated Entamoeba histolytica Infection and Inflammatory Bowel Disease. MBio. 2018 Sep 18;9(5). doi: 10.1128/mBio.01668-18. PubMed PMID: 30228239; PubMed Central PMCID: PMC6143743.
Projects
Population Architecture using Genomics and Epidemiology
Genome Sequencing Program
Clinical Genome Resource (ClinGen)