Departmental Affiliations
Research Interests
kidney;biomarkers;acute kidney injury;diabetic kidney disease;CKD;AKI
Experiences & Accomplishments
Education
PhD
University of Colorado Health Sciences Center
2003
MD
Seth G.S. Medical College and KEM Hospital
1996
Overview
Dr. Chirag R. Parikh is a Professor of Medicine and the Director of the Division of Nephrology at Johns Hopkins University School of Medicine. Originally from India, Dr. Parikh attended medical school at the Seth G.S. Medical College and KEM Hospital in Mumbai. He then completed his internal medicine residency at the Nassau University Medical Center and SUNY at Stony Brook in New York, followed by his fellowship in Nephrology and Hypertension and UNOS Transplant Certification at the University of Colorado. While completing his fellowship, he also earned a doctorate in Clinical Investigation. Following this fellowship, he joined the Yale School of Medicine as the Director of the Program of Applied Translational Research, a Professor of Medicine and Investigative Medicine, and Professor of Medicine at the Clinical Epidemiology Research Center in the VA Connecticut Health Care System.
Dr. Parikh has several active NIH grants and has published over 250 original articles, which have been cited over 25,000 times in literature. His research focuses on the translation and validation of novel biomarkers for the diagnosis and prognosis of acute kidney injury and diabetic kidney disease, and his studies have refined the clinical definitions of perioperative acute kidney injury and hepatorenal syndrome, have developed strategies to reduce kidney discard in deceased donor transplantation, and have advanced regulatory approvals of kidney injury biomarkers. He has also developed biomarkers to identify rapid progressors of early diabetic kidney disease before derangements in serum creatinine. Dr. Parikh’s research goal is to translate our understanding of pathophysiological mechanisms into clinical practice and to improve outcomes in patients with kidney disease.
Dr. Parikh has several active NIH grants and has published over 250 original articles, which have been cited over 25,000 times in literature. His research focuses on the translation and validation of novel biomarkers for the diagnosis and prognosis of acute kidney injury and diabetic kidney disease, and his studies have refined the clinical definitions of perioperative acute kidney injury and hepatorenal syndrome, have developed strategies to reduce kidney discard in deceased donor transplantation, and have advanced regulatory approvals of kidney injury biomarkers. He has also developed biomarkers to identify rapid progressors of early diabetic kidney disease before derangements in serum creatinine. Dr. Parikh’s research goal is to translate our understanding of pathophysiological mechanisms into clinical practice and to improve outcomes in patients with kidney disease.
Honors & Awards
American Society of Nephrology–American Heart Association Young Investigator Award 2017
Member of the American Society of Clinical Investigation 2017
American Nephrologists of Indian Origin Academic Excellence Award (ANIO) 2018
Member of the American Society of Clinical Investigation 2017
American Nephrologists of Indian Origin Academic Excellence Award (ANIO) 2018
Select Publications
Most recent publications
- Parikh CR, Liu C, Mor MK, Palevsky PM, Kaufman JS, Thiessen Philbrook H, Weisbord SD. Kidney Biomarkers of Injury and Repair as Predictors of Contrast-Associated AKI: A Substudy of the PRESERVE Trial. Am J Kidney Dis. 2019; pii: S0272-6386(19)30886-8. [PMID 31547939]
- Parikh CR, Greenberg JH, McArthur E, Thiessen-Philbrook H, Everett AD, Wald R, Zappitelli M, Chanchlani R, Garg AX. Incidence of ESKD and Mortality among Children with Congenital Heart Disease after Cardiac Surgery. Clin J Am Soc Nephrol. 2019 7; 14(10):1450-1457. [PMID 31501090]
- Hsu CY, Chinchilli VM, Coca S, Devarajan P, Ghahramani N, Go AS, Hsu RK, Ikizler TA, Kaufman J, Liu KD, Parikh CR, Reeves WB, Wurfel M, Zappitelli M, Kimmel PL, Siew ED; ASSESS-AKI Investigators. Post-Acute Kidney Injury Proteinuria and Subsequent Kidney Disease Progression: The Assessment, Serial Evaluation, and Subsequent Sequelae in Acute Kidney Injury (ASSESS-AKI) Study. JAMA Intern Med. 2020;180(3):402-10. doi:10.1001/jamainternmed.2019.6390. Online ahead of print. [PMID: 31985750]
- Parker DM, Everett AD, Stabler ME, Jacobs ML, Jacobs JP, Vricella L, Thiessen-Philbrook H, Parikh CR, Manlhiot C, Brown JR. ST2 Predicts Risk of Unplanned Readmission Within One Year After Pediatric Congenital Heart Surgery. Ann Thorac Surg. 2020; S0003-4975(20)30431-8. doi: 10.1016/j.athoracsur.2020.02.056. Online ahead of print. [PMID: 32246937]
- Chen TK, Parikh CR. Management of Presumed Acute Kidney Injury During Hypertensive Therapy: Stay Calm and Carry On? Am J Nephrol. 2020;51(2):108-115. doi: 10.1159/000505447. Epub 2020 Jan 15. [PMID: 31940606]