Lauren Allen, DrPH ’21, specializes in clinical research administration in the domains of policy setting and implementation, management of multi-institutional research, and knowledge dissemination.
clinical research; research administration; research operations; data quality assurance; multi-center studies; randomized controlled trials; observational studies; injury research; minimizing threats to validity in studies involving primary data collection; large pragmatic trials
Experiences & Accomplishments
Lauren E. Allen, DrPH ‘21, MA is a Research Associate at the Bloomberg School of Public Health, Department of Health Policy & Management. She is a public health practitioner in the research administration setting. She currently serves as the Director of Operations for the Major Extremity Trauma Research Consortium (METRC), a large multicenter clinical trials consortium in orthopaedic trauma. Dr. Allen’s expertise is in the domains of policy setting and implementation; management of multi-institutional research; and knowledge dissemination. She is a thought leader and the architect of METRC’s robust infrastructure. The consortium has supported more than 35 multicenter trials in a network of more than 80 trauma centers throughout the United States and Canada. She also provides overall direction for the METRC project which develops Clinical Practice Guidelines and Appropriate Use Criteria for topics of relevance to METRC's research agenda and which incorporate evidence produced by published METRC trials.
As an extension of her METRC work and role, Dr. Allen is also a co-investigator on a large, complex, two phased pragmatic multicenter study of non-opioid treatments for knee osteoarthritis pain- the SKOAP Study. This project is funded by the NIH’s Helping End Addition Long Term (HEAL) Initiative, the largest federal investment in the opioid crisis. Dr. Allen has adapted many of METRC’s programs for the SKOAP Consortium and integrated the METRC management approach with that of the NIH-NCAT’s Trial Innovation Network (TIN), a group of nationwide centers of excellence with expertise in specific components of clinical trial management and implementation.
Honors & Awards
“The Major Extremity Trauma Research Consortium (METRC): Development and Impact of an Orthopaedic Trauma Research Program”, 2023 Elizabeth Winston Lanier Kappa Delta Award (as member of METRC Coordinating Center)
Publications pertaining to METRC
Building a Clinical Research Network in Trauma Orthopaedics. The Major Extremity Trauma Research Consortium (METRC). J Orthop Trauma. 2016. 30(7):353-61
The Major Extremity Trauma Research Consortium (METRC). Effect of Intrawound Vancomycin Powder in Operatively Treated High-risk Tibia Fractures: A Randomized Clinical Trial. JAMA Surg. Published online March 24, 2021. doi:10.1001/jamasurg.2020.7259
Major Extremity Trauma Research Consortium (METRC). Effect of Supplemental Perioperative Oxygen on SSI Among Adults with Lower-Extremity Fractures at Increased Risk for Infection: A Randomized Clinical Trial. J Bone Joint Surg. 2022; 104(14):1236-1243. doi: 10.2106/JBJS.21.01317
Major Extremity Trauma Research Consortium (METRC). Modern External Ring Fixation Versus Internal Fixation for Treatment of Severe Open Tibial Fractures. J Bone Joint Surg. 2022;104(12):1061-1067. doi: 10.2106/JBJS.21.01126
Major Extremity Trauma Research Consortium (METRC). Outcomes Following Severe Distal Tibial, Ankle, and/or Mid/Hindfoot Trauma: Comparison of Limb Salvage and Transtibial Amputation (OUTLET) [published online ahead of print, 2021 May 12]. J Bone Joint Surg Am. 2021;10.2106/JBJS.20.01320. doi:10.2106/JBJS.20.01320