David Dowdy, MD, PhD '08, ScM ’02, studies the implementation of interventions to fight tuberculosis, the world's most deadly infectious disease.
infectious diseases; tuberculosis; HIV; epidemiology; mathematical modeling; implementation science; infectious disease dynamics; health economics
Experiences & Accomplishments
Johns Hopkins School of Medicine
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
I am a mid-career investigator in the field of infectious disease epidemiology, and also a practicing general internist. My interdisciplinary research lies at the nexus of infectious disease modeling, health economics, operational and implementation science, and classical epidemiology. My primary interests are: (1) Dynamic modeling and economic evaluation of TB and TB/HIV: My greatest research passion is evaluating the implementation and scale-up of TB and HIV control interventions, especially diagnostic and case-finding strategies. I combine methods from traditional epidemiology, cost-effectiveness analysis, and epidemic modeling with the aim of answering questions of relevance to patients and policy-makers. I serve on the steering committee of the Gates Foundation-funded TB-Modeling and Analysis Consortium (TB-MAC) and direct two NIH-funded projects related to modeling the scale-up of TB diagnostic tests. I currently work with collaborators on projects based in Malawi, South Africa, Uganda, India, Zambia, Brazil, Canada, and the United States. (2) Translational epidemiology: I have great interest in creating modeling frameworks that allow decision-makers to translate epidemiological data into effective decisions. I welcome collaboration from researchers, clinicians, or students having expertise in any field, who hope to create models to translate epidemiological data into meaningful policy, practical, or clinical decisions. (3) Implementation science: I am interested not only in how interventions operate in idealized settings, but also improving how they are implemented in the real world. Generally, implementation barriers are greater than theoretical scientific ones; I think it is critical to conduct research that will help us overcome them. (4) Teaching and mentorship: These are essential, and often-undervalued, skills in the field of epidemiology. If our profession is to continue its record of success, I firmly believe that we need to train future leaders how to teach and mentor others, and also to do our best to serve as role models in that regard.
Honors & Awards
Awards since 2008: 2020 JHU Catalyst Award recipient 2018 Advising, Mentoring, and Teaching Recognition Award (AMTRA), JHSPH 2015 Excellence in Mentoring Award 2014 Golden Apple Teaching Award (large class) 2013 Advising, Mentoring, and Teaching Recognition Award (AMTRA), JHSPH 2012 B. Frank and Kathleen Polk Assistant Professor of Epidemiology 2012 Young Investigator Prize, International Union Against Tuberculosis and Lung Disease 2011 Tom Evans Teaching Award, Internal Medicine Residency Program, UCSF 2010 Diane Becker Award in Clinical Epidemiology and Prevention, Johns Hopkins GIM Housestaff Research Award 2010 Floyd Rector Clinical Science Research Award, Internal Medicine Residency Program, UCSF 2010 Teaching Excellence Award for Cherished Housestaff (TEACH), UCSF School of Medicine 2009 Julius Krevans Award for Outstanding Housestaff Service, San Francisco General Hospital 2008 Warfield T. Longcope Prize in Clinical Medicine, Johns Hopkins University School of Medicine 2008 David E. Rogers Award for Professionalism, Ethics, & Community, Johns Hopkins University School of Medicine 2008 Alpha Omega Alpha Honor Society 2008 Arthur M. Dannenberg, Jr. Award for Tuberculosis Research
Major first/senior author publications in Jan-June 2020:
- Jo Y, Shrestha S, Gomes I, Marks S, Hill A, Asay G, Dowdy D. Model-Based Cost-Effectiveness of State-level Latent Tuberculosis Interventions in California, Florida, New York and Texas. Clin Infect Dis. 2020 Jun 25:ciaa857. doi: 10.1093/cid/ciaa857. Epub ahead of print.
- Robsky KO, Kitonsa PJ, Mukiibi J, Nakasolya O, Isooba D, Nalutaaya A, Salvatore PP, Kendall EA, Katamba A, Dowdy D. Spatial distribution of people diagnosed with tuberculosis through routine and active case finding: a community-based study in Kampala, Uganda. Infect Dis Poverty. 2020 Jun 22;9(1):73. doi: 10.1186/s40249-020-00687-2.
- Dowdy DW, Powers KA, Hallett TB. Towards evidence-based integration of services for HIV, non-communicable diseases and substance use: insights from modelling. J Int AIDS Soc. 2020 Jun;23 Suppl 1(Suppl 1):e25525. doi: 10.1002/jia2.25525.
- Dowdy DW, Zwerling AA, Stennett A, et al. Measuring Stigma to Assess the Social Justice Implications of Health-Related Policy Decisions: Application to Novel Treatment Regimens for Multidrug-Resistant Tuberculosis. MDM Policy Pract. 2020;5(1):2381468320915239. doi:10.1177/2381468320915239
- Shin H, Ngwira LG, Tucker A, Chaisson RE, Corbett EL, Dowdy DW. Patient-incurred cost of inpatient treatment for Tuberculosis in rural Malawi. Trop Med Int Health. 2020 May;25(5):624-634. doi: 10.1111/tmi.13381.
Impact of Hotspot-Targeted Vaccine Strategies
TB Modelling and Analysis Consortium (TB-MAC)
A User-Friendly Epidemic-Economic Model of Diagnostic Tests for Tuberculosis
Comparative Cost-Effectiveness of TB Contact Tracing in Geographic
Comparative Effectiveness of Rapid TB Diagnostics in Uganda
Comparative Effectiveness of TB Diagnostics in Uganda
Comparative Effectiveness/Implementation of TB Case Finding in Rural South...
Epidemiological Impact of Geographically Targeted Strategies
Impact of TB Prevention in New York City
Modeling the public health impact, affordability and cost-effectiveness of HIV
Modeling the Reproducibility of Blood Assays for TB Infection
Pathways to Private-Sector TB Diagnosis in India
UCSF-GIVI Center for AIDS Research
User-Friendly Models of TB Diagnostic Strategies
WO 10: Modeling Impact for Novel TB Drug Regimens
Kharituwe: Innovative Contact Tracing Strategies for Mobile Populations in South Africa
STOMP TB: An evaluation of TB transmission in urban Uganda
Modeling TB hotspots and transmission potential in Dhaka
Modeling the laboratory network for diagnosis of infectious diseases in Ghana
3HP Options: A trial of options for TB preventive therapy in Uganda
Simulation of HIV Epidemic among Baltimore’s MSM
Cost-effectiveness of comparing two Intervention Mapping implementation approaches for improving ART adherence among PWID in Vietnam.
Ultra Curto TB