Departmental Affiliations
Center & Institute Affiliations
Contact Info
615 N. Wolfe Street, Room E6148
Baltimore
Maryland
21205
US
Research Interests
Cancer;
Prostate;
Colorectal;
Epidemiology;
Modifiable risk factors;
Biomarkers of risk and prognosis;
Etiology;
Prevention;
Early Detection;
Screening;
Experiences & Accomplishments
Education
PhD
Saint Louis University
2008
MPH
Saint Louis University
2007
MA
Boston University
2002
BA
Washington University in St. Louis
1998
Overview
Dr. Joshu is a cancer epidemiologist. She is the Director of the Master's Program in the Department of Epidemiology. She is also a member of the Cancer Prevention and Control Program at the Sidney Kimmel Comprehensive Cancer Center (SKCCC) at Johns Hopkins.
Dr. Joshu's research examines the role of modifiable risk factors, in particular obesity, on cancer incidence and outcomes. With this work, she aims to (1) inform our understanding of the biological mechanisms that underlie these associations, and (2) translate these findings into clinically useful strategies to prevent disease and/or poor outcomes among those with cancer. She conducts both population-based and tissue-based research to address these questions. Dr. Joshu also conducts research to identify opportunities to improve cancer prevention and treatment across the lifespan with particular focus on residents of the Baltimore region and people with HIV.
Dr. Joshu is an active participant in several multidisciplinary studies on cancer etiology, prevention, and control. Dr. Joshu co-leads the Atherosclerosis Risk in Communities (ARIC) Study Cancer Working Group, and co-directed the effort to enhance ARIC’s infrastructure for cancer research. To facilitate the conduct of tissue-based research in population-based studies, she established a tissue repository for Washington County ARIC participants and participants of two long-standing Washington County cancer cohorts, CLUE I and CLUE II, which includes specimens from ~1,800 ARIC participants and ~9,300 CLUE I and CLUE II participants. She has also partnered with leadership of Johns Hopkins Community Physicians (JHCP) and the Baltimore City Health Department to identify opportunities to improve cancer prevention, including HPV vaccination and colorectal and lung cancer screening, in the Baltimore region.
Dr. Joshu's research examines the role of modifiable risk factors, in particular obesity, on cancer incidence and outcomes. With this work, she aims to (1) inform our understanding of the biological mechanisms that underlie these associations, and (2) translate these findings into clinically useful strategies to prevent disease and/or poor outcomes among those with cancer. She conducts both population-based and tissue-based research to address these questions. Dr. Joshu also conducts research to identify opportunities to improve cancer prevention and treatment across the lifespan with particular focus on residents of the Baltimore region and people with HIV.
Dr. Joshu is an active participant in several multidisciplinary studies on cancer etiology, prevention, and control. Dr. Joshu co-leads the Atherosclerosis Risk in Communities (ARIC) Study Cancer Working Group, and co-directed the effort to enhance ARIC’s infrastructure for cancer research. To facilitate the conduct of tissue-based research in population-based studies, she established a tissue repository for Washington County ARIC participants and participants of two long-standing Washington County cancer cohorts, CLUE I and CLUE II, which includes specimens from ~1,800 ARIC participants and ~9,300 CLUE I and CLUE II participants. She has also partnered with leadership of Johns Hopkins Community Physicians (JHCP) and the Baltimore City Health Department to identify opportunities to improve cancer prevention, including HPV vaccination and colorectal and lung cancer screening, in the Baltimore region.
Honors & Awards
Delta Omega Honorary Public Health Society, Alpha Delta Chapter
Martin D. Abeloff, MD Scholar-in-Training in Cancer Prevention and Control, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine
Martin D. Abeloff, MD Scholar-in-Training in Cancer Prevention and Control, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine
Select Publications
Recent Publications
- Joshu CE, Barber JR, Coresh J, Couper DJ, Mosley TH, Vitolins MZ, Butler KR, Nelson HH, Prizment AE, Selvin E, Tooze JA, Visvanathan K, Folsom AR, Platz EA. Enhancing the Infrastructure of the Atherosclerosis Risk in Communities (ARIC) Study for Cancer Epidemiology Research: ARIC Cancer. Cancer Epidemiol Biomarkers Prev. 2018 27(3):295-305.
- Huang BZ, Tsilidis KK, Smith MW, Hoffman-Bolton J, Visvanathan K, Platz EA, Joshu CE. Polymorphisms in genes related to inflammation and obesity and colorectal adenoma risk. Mol Carcinog. Mol Carcinog. 2018. May 26. Epub ahead of print
- Clarke MA, Joshu CE. Early-Life Exposures and Adult Cancer Risk. Epidemiol Rev. 2017. Epidemiol Rev. 2017 Jan 1;39(1):11-27.
- Joshu CE, Peskoe SB, Heaphy CM, Kenfield SA, Van Blarigan EL, Mucci LA, Giovannucci E, Stampfer MJ, Yun GS, Lee T, Hicks JL, De Marzo AM, Meeker AK, Platz EA. Pre-diagnostic obesity and inactivity are associated with shorter telomere length in prostate stromal cells. Cancer Prev Res. 2015. Cancer Prev Res. 8(8):737-42.
- Joshu CE, Peskoe SB, Heaphy CM, Kenfield SA, Mucci LA, Giovannucci EL, Stampfer MJ, Yoon G, Lee TK, Hicks JL, De Marzo AM, Meeker AK, Platz EA. Current or recent smoking is associated with more variable telomere length in prostate stromal cells and prostate cancer cells. 2017. Prostate. 2018 78(3):233-238.
Projects
ARIC Cancer