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Principles of Clinical Epidemiology

East Baltimore
2nd Term
Academic Year
2024 - 2025
Instruction Method
Class Time(s)
Tuesday, 8:00 - 10:20am
Auditors Allowed
Yes, with instructor consent
Available to Undergraduate
Grading Restriction
Letter Grade or Pass/Fail
Course Instructor(s)
Contact Name
Frequency Schedule
Every Year

340.751 (Epidemiologic Methods 1)

Presents lectures and interactive sessions designed to expose students to basic principles of clinical epidemiology and introduce key methods utilized in clinical outcomes research. Focuses on principles and methods in clinical epidemiology which would be most utilized by clinicians/clinician researchers for screening and diagnosis of illness as well as for prognostication and decision-making.
Learning Objectives
Upon successfully completing this course, students will be able to:
  1. Describe how epidemiological methods are applied to medicine and how scientific evidence drive decision on clinical practice.
  2. Draw a ROC curve to understand and estimate the effect and implications of different cutoff points in diagnostic test
  3. Evaluate the performance of diagnostic tests taking into account characteristics of the test (sensitivity, specificity, etc.), potential outcomes and the features of the population (prevalence of disease and risk factors)
  4. Describe key factors for deciding optimal outcome measures for a clinical study
  5. Describe advantages and disadvantages of clinical trials and observational studies for evaluating treatment effects
  6. Build a decision analysis tree based on probabilities and see how different outcomes influence the decision making in clinical settings
Methods of Assessment
This course is evaluated as follows:
  • 15% Participation
  • 60% Homework
  • 25% Final Project