120.600.81
Biochemistry I: Protein Structure and Enzyme Catalysis
Location
Internet
Term
1st Term
Department
Biochemistry and Molecular Biology
Credit(s)
3
Academic Year
2024 - 2025
Instruction Method
Asynchronous Online
Auditors Allowed
Yes, with instructor consent
Available to Undergraduate
No
Grading Restriction
Letter Grade or Pass/Fail
Course Instructor(s)
Contact Name
Frequency Schedule
Every Year
Resources
Prerequisite
Students should have a background in general and organic chemistry
Covers the physical and chemical properties of the amino acids, the various elements of protein structure, and the cooperative behavior of multimeric proteins. Explore the kinetics of enzyme-catalyzed reactions, and the active site mechanisms of representative classes of enzymes. Describes the molecular basis of action for selected enzyme inhibitor-based drugs.
Learning Objectives
Upon successfully completing this course, students will be able to:
- Compare and contrast the physical and chemical properties of amino acids
- Describe the primary, secondary, and tertary elements of protein structures
- Explain the molecular basis for the cooperative behavior of multimeric proteins
- Determine and interpret the steady state kinetics of enzyme catalyzed reactions
- Describe the active site mechanisms of representative classes of enzymes
- Explain how irreversible and reversible enzyme inhibitors are being used as drugs
Methods of Assessment
This course is evaluated as follows:
- 33% Exam(s)
- 33% Exam(s)
- 33% Exam(s)
Enrollment Restriction
No BMB PhD students should enroll