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Principles of Immunology I

East Baltimore
1st Term
Molecular Microbiology and Immunology
Academic Year
2023 - 2024
Instruction Method
Class Time(s)
Tu, Th, 8:30 - 10:20am
Auditors Allowed
Yes, with instructor consent
Available to Undergraduate
Grading Restriction
Letter Grade or Pass/Fail
Course Instructor(s)
Contact Name
Frequency Schedule
Every Year
Next Offered
2024 - 2025

Although there is no specific prerequisite course, recent formal course work in in two or more of the following is highly recommended: molecular biology, biochemistry, cell biology, and genetics

Introduces biological concepts of immunology; molecular nature of antigens; molecular basis for antibody and T-cell receptor structure and diversity; complement; hypersensitivity reactions; cellular basis for the immune response; cell-mediated immunity; adhesion molecules and coreceptors cell activation; cytokines and other soluble mediators; major histocompatibility complex (MHC) antigens; tumor immunology; transplantation immunobiology; mechanisms of resistance to microorganisms; tolerance; autoimmunity; and immuno-deficiency.
Learning Objectives
Upon successfully completing this course, students will be able to:
  1. Define the tissue, cellular and molecular components that constitute the vertebrate innate and adaptive immune system
  2. Explain the generation of lymphocyte antigen receptors and the molecular and cellular basis for diversity and specificity of receptors on immune cells
  3. Define the basis for antigen presentation to T cells
  4. Define the basis for recognition of self and non-self recognition
  5. Define the development and survival of lymphocytes
  6. Explain the major signaling pathways used by immune cells
  7. Define T cell-mediated and B cell-mediated immunity
Methods of Assessment
This course is evaluated as follows:
  • 50% Midterm
  • 50% Final Exam
Special Comments

Required for MMI PhD students.