Public Health Toxicology
PH.180.601 or PH.180.609 required. Background in organic chemistry and/or biochemistry and cell biology useful.
- Describe the basic toxicokinetic principles that determine how various classes of environmentally important chemicals interact with molecules in cells, tissues and organs to cause adverse effects
- Describe the basic toxicodynamic processes that can alter normal cell, tissue and organ functions resulting in adverse effects
- Explain the importance of dose-response in determining the adverse effects of chemicals and the different dose response models for non-carcinogens and carcinogens
- Provide examples of underlying genetic and social susceptibility factors that contribute to the ability of chemicals to elicit effects that contribute to human disease
- Explain how evidence based on quantitative assessment of local, national and global cancer incidence data contributes to identification of susceptible populations, points to possible causative factors and suggests approaches to preventive interventions
- Illustrate how the use of biomarkers and primary, secondary and tertiary prevention and can come together to facilitate prevention of human disease
- Explain the science underlying toxicity testing for the ability of chemicals to elicit adverse human health effects
- Explain the risk assessment process and the role of toxicity testing and human epidemiology in it
- Apply evidence from toxicity testing and human epidemiology studies to calculate an acceptable daily exposure (RfD)
- Apply the toxicological concepts to specific chemicals to which people are exposed
- 61% Four Exams
- 18% Four Quizzes
- 21% Written Assignment(s)
The deadline to add this course is September 7 due to a group project assignment.
Background in organic chemistry and/or biochemistry and cell biology useful.