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Research Article Receives Peer Award


A recent study by Barry Zirkin, PhD, a professor in the Johns Hopkins Bloomberg School of Public Health¹s Department of Biochemistry andMolecular Biology, and his PhD student, Erin Stanley, PhD, now a postdoctoral fellow at Mayo Clinic, was recognized by the Faculty of 1000 (F1000) for significant contributions to biomedical research. Zirkin’s article, “Stem Leydig Cell Differentiation: Gene Expression During Development of the Adult Rat Population of Leydig Cells” was published in the August 10, 2011 edition of the journal Biology of Reproduction.

The article was selected and evaluated by F1000 faculty member Gary Klinefelter. F1000 said that the selection places Zirkin’s work in a library of the top 2 percent of published articles in biology and medicine.

“This manuscript represents a significant contribution both in terms of level of effort and novel data” Klinefelter wrote of the study’s attempt to characterize the Leydig cell lineage from precursor stem cells to adult Leydig cells. “These data lay the foundation for important new markers of the Leydig cell throughout reproductive development. Such markers would be tremendously valuable to toxicologists studying the effects of chemical exposures throughout reproductive development."

Since 2002, F1000 has identified and evaluated the most important articles in biology and medical research publications. Articles are selected by leading scientists and clinicians who rate and explain the importance of selected articles.

The full evaluation is available at