260.714.01
Immunogenetics
Course Status
Discontinued
Course Status
Discontinued
Location
East Baltimore
Term
4th Term
Department
Molecular Microbiology and Immunology
Credit(s)
3
Academic Year
2014 - 2015
Instruction Method
TBD
Tu, Th, 1:30 - 2:50pm
Auditors Allowed
Yes, with instructor consent
Available to Undergraduate
No
Grading Restriction
Letter Grade or Pass/Fail
Contact Name
Frequency Schedule
Every Other Year
Resources
Prerequisite
260.611-612 or introductory course in immunology; introductory course in genetics
Presents the genetic basis of immune responsiveness. Reviews the genetic mechanisms responsible for generation of diversity in the genes for immunoglobulins, the T cell receptor molecules, the major histocompatibility molecules, and other key molecules of the immuno-globulin superfamily. Discusses mechanisms and statistical evaluation of immunogenetic associations with susceptibility or resistance to disease.
Learning Objectives
Upon successfully completing this course, students will be able to:
- Define the genetic systems that encode molecules with integral roles in immune regulation
- Assess the impact of allelic polymorphism in certain genes on features such as gene expression and MHC restriction
- Define the basic mechanisms for expansion of the immunologic repertoire of antigen receptors
- Understand the implications of population differences in the frequencies of genes involved in immune responses