260.608.01
Advanced Topics in AIDS Research
Course Status
Cancelled
Course Status
Cancelled
Location
East Baltimore
Term
4th Term
Department
Molecular Microbiology and Immunology
Credit(s)
4
Academic Year
2014 - 2015
Instruction Method
TBD
Available to Undergraduate
No
Grading Restriction
Letter Grade or Pass/Fail
Course Instructor(s)
Xiaofang Yu
Frequency Schedule
Every Other Year
Resources
Prerequisite
PH 260.623 or instructor consent
Introduces students to the HIV lifecycle and the molecular events occurring during productive infection. Covers topics including the HIV life cycle (Entry, Reverse transcription, Integration, Assembly, Budding, and Maturation), viral regulatory proteins, host innate anti-HIV responses (Apobec and Trim5á), immune responses induced by vaccine and infection, recent progress in HIV vaccine development, origins of HIV, SIV, endogenous retroviruses, new insights in HIV pathogenesis, host factors influencing disease outcome, latency and persistence, transmission, and prophylactic strategies of prevention.
Learning Objectives
Upon successfully completing this course, students will be able to:
- Define points of the viral lifecycle at which host proteins interfere with viral infection
- Understand replication cycle of HIV and contrast with other retroviruses
- Assess current vaccine strategies
- Analyze current literature
- Explain the influence of host factors on disease outcome