260.611.01
Principles of Immunology I
Location
East Baltimore
Term
1st Term
Department
Molecular Microbiology and Immunology
Credit(s)
4
Academic Year
2013 - 2014
Instruction Method
TBD
Tu, Th, 8:30 - 10:20am
Available to Undergraduate
No
Grading Restriction
Letter Grade or Pass/Fail
Course Instructor(s)
Frequency Schedule
Every Year
Resources
Prerequisite
A course in advanced biology
Introduces biological concepts of immunology; molecular nature of antigens; molecular basis for antibody and T-cell receptor structure and diversity; complement; hypersensitivity reactions; cellular basis for the immune response; cell-mediated immunity; adhesion molecules and coreceptors cell activation; cytokines and other soluble mediators; major histocompatibility complex (MHC) antigens; tumor immunology; transplantation immunobiology; mechanisms of resistance to microorganisms; tolerance; autoimmunity; and immuno-deficiency.
Learning Objectives
Upon successfully completing this course, students will be able to:
- Define the tissue, cellular and molecular components that constitute the vertebrate innate and adaptive immune system
- Explain the generation of lymphocyte antigen receptors and the molecular and cellular basis for diversity and specificity of receptors on immune cells
- Define the basis for antigen presentation to T cells
- Define the basis for recognition of self and non-self recognition
- Define the development and survival of lymphocytes
- Explain the major signaling pathways used by immune cells
- Define T cell-mediated and B cell-mediated immunity
Required for MMI students.