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RESEARCH

Discovery Research in Laboratories in Baltimore and Field Research in Malaria-Endemic Countries

The biology of malaria is complex and involves three interacting organisms: the malaria parasite Plasmodium, the Anopheles mosquito vector, and the human host. Our researchers comprehensively study a variety of the biological aspects of malaria. By targeting these interactions they can stop the transmission of the disease. 

Areas of Study 

Entomology  

Our scientists study the population biology of mosquito disease vectors and their molecular interaction with human pathogens, focusing on the Plasmodium parasite that causes malaria.


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Parasitology

Our investigators study the cellular and molecular events that enable the malaria parasite to live and replicate in its mosquito and mammalian hosts. 

 

 

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Vaccines

Our work in immunology and vaccine development evaluates new vaccine targets and platforms helping pave the way for more effective vaccines.

 

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Epidemiology 

Our researchers are looking at the epidemiology of malaria at fieldsites in Zambia and other malaria-endemic countries in sub-Saharan Africa, India, and elsewhere.

 

 

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At-a-Glance | Labs

The Dimopoulos Lab 

Mosquitoes that transmit human pathogens 

The Sinnis Lab 

The infective stage of the malaria parasite, sporozoites

The Jacobs-Lorena Lab

Gene-editing for malaria control in the mosquito  

The McMeniman Lab 

Mosquito attraction to human scent  

Sean Prigge

The Prigge Lab 

Malaria apicoplast and mitochondrial proteins 

David Sullivan

The Sullivan Lab 

Malaria diagnosis and therapeutics 

Theresa Shapiro, MD

The Shapiro Lab

Preclinical and clinical pharmacology of new drugs for malaria

Prakash Srinivasan

The Srinivasan Lab

Malaria parasites invasion of host cells

Debbie Andrew

The Andrew Lab

Fidel Zavala

The Zavala Lab

Mechanisms underlying the induction of protective T-cell mediated immunity ag. malaria parasites

Chris Potter

The Potter Lab

Researches Anopheles gambiae and how they use their sense of smell (olfaction) to find humans from a distance

The Norris Lab

Research focuses on genetic diversity within, and the genetic structuring of, arthropod and arthropod-borne pathogen populations