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RESEARCH

Discovery Research in Laboratories in Baltimore and Field Research in Malaria-Endemic Countries

The biology of malaria is complex and involves three interacting organisms: the malaria parasite Plasmodium, the Anopheles mosquito vector, and the human host. Our researchers comprehensively study a variety of the biological aspects of malaria. By targeting these interactions they can stop the transmission of the disease. 

Areas of Study 

Entomology  

Our scientists study the population biology of mosquito disease vectors and their molecular interaction with human pathogens, focusing on the Plasmodium parasite that causes malaria.


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Parasitology

Our investigators study the cellular and molecular events that enable the malaria parasite to live and replicate in its mosquito and mammalian hosts. 

 

 

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Vaccines

Our work in immunology and vaccine development evaluates new vaccine targets and platforms helping pave the way for more effective vaccines.

 

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Epidemiology 

Our researchers are looking at the epidemiology of malaria at fieldsites in Zambia and other malaria-endemic countries in sub-Saharan Africa, India, and elsewhere.

 

 

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At-a-Glance | Labs

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Deborah Andrew, PhD

Salivary gland biology

Jane Carlton, Director, JHMRI

Jane Carlton, PhD

Genomics; systems biology; malaria; Plasmodium; Anopheles; India; infectious diseases; Trichomonas

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Isabelle Coppens, PhD

Toxoplasma; Plasmodium liver stage; Cryptosporidium; host cell-parasite interactions.

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George Dimopoulos, PhD

Mosquitoes that transmit human pathogens 

Matthew Ippolito, MD, PhD

Project Lead: Southern Africa ICEMR, International Centers of Excellence for Malaria Research

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Marcelo Jacobs-Lorena, PhD

Gene-editing for malaria control in the mosquito  

Conor McMeniman, PhD

Mosquito attraction to human scent  

William Moss, MD

William Moss, MD

Principal Investigator: Southern Africa ICEMR, International Centers of Excellence for Malaria Research

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Douglas Norris, PhD

Research focuses on genetic diversity within, and the genetic structuring of, arthropod and arthropod-borne pathogen populations

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Chris Potter, PhD

Researches Anopheles gambiae and how they use their sense of smell (olfaction) to find humans from a distance

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Sean Prigge, PhD

Malaria apicoplast and mitochondrial proteins 

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Theresa Shapiro, MD

Preclinical and clinical pharmacology of new drugs for malaria

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Photini Sinnis, MD

The infective stage of the malaria parasite, sporozoites

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Prakash Srinivasan, PhD

Malaria parasites invasion of host cells

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David Sullivan, MD

Malaria diagnosis and therapeutics 

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Fidel Zavala, PhD

Mechanisms underlying the induction of protective T-cell mediated immunity ag. malaria parasites