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PCV Impact Assessment


Sylhet District, Bangladesh


This study in Sylhet district, Bangladesh, will evaluate the effectiveness of a 10-valent pneumococcal conjugate vaccine (PCV) against invasive disease. 

Study Objectives

  • Measure the rate of invasive (culture confirmed) pneumococcal disease (IPD) in the population before introduction of the PCV vaccine
  • Measure the impact on clinical pneumonia, IPD, x-ray and ultrasound-confirmed pneumonia
  • Measure the impact of PCV on nasopharyngeal carriage with Streptococcus Pneumoniae
  • The study uses incidence trend and case-control study designs

Key Facts

Principal Investigator

Abdullah H. Baqui, JHSPH 

Local Principal Investigator

Abdul Quaiyum, ICDDR,B


  • Bill & Melinda Gates Foundation
  • GlaxoSmithKline

Study Team

Projahnmo Study Group in Bangladesh