RESEARCH
Discovery Research in Laboratories in Baltimore and Field Research in Malaria-Endemic Countries
The biology of malaria is complex and involves three interacting organisms: the malaria parasite Plasmodium, the Anopheles mosquito vector, and the human host. Our researchers comprehensively study a variety of the biological aspects of malaria. By targeting these interactions they can stop the transmission of the disease.
Areas of Study
Entomology
Our scientists study the population biology of mosquito disease vectors and their molecular interaction with human pathogens, focusing on the Plasmodium parasite that causes malaria.
Parasitology
Our investigators study the cellular and molecular events that enable the malaria parasite to live and replicate in its mosquito and mammalian hosts.
Vaccines
Our work in immunology and vaccine development evaluates new vaccine targets and platforms helping pave the way for more effective vaccines.
Epidemiology
Our researchers are looking at the epidemiology of malaria at fieldsites in Zambia and other malaria-endemic countries in sub-Saharan Africa, India, and elsewhere.
At-a-Glance | Labs
Jane Carlton, PhD
Genomics; systems biology; malaria; Plasmodium; Anopheles; India; infectious diseases; Trichomonas
Isabelle Coppens, PhD
Toxoplasma; Plasmodium liver stage; Cryptosporidium; host cell-parasite interactions.
George Dimopoulos, PhD
Mosquitoes that transmit human pathogens
Matthew Ippolito, MD, PhD
Project Lead: Southern Africa ICEMR, International Centers of Excellence for Malaria Research
Marcelo Jacobs-Lorena, PhD
Gene-editing for malaria control in the mosquito
Conor McMeniman, PhD
Mosquito attraction to human scent
William Moss, MD
Principal Investigator: Southern Africa ICEMR, International Centers of Excellence for Malaria Research
Douglas Norris, PhD
Research focuses on genetic diversity within, and the genetic structuring of, arthropod and arthropod-borne pathogen populations
Chris Potter, PhD
Researches Anopheles gambiae and how they use their sense of smell (olfaction) to find humans from a distance
Theresa Shapiro, MD
Preclinical and clinical pharmacology of new drugs for malaria
Photini Sinnis, MD
The infective stage of the malaria parasite, sporozoites
Fidel Zavala, PhD
Mechanisms underlying the induction of protective T-cell mediated immunity ag. malaria parasites