This resource provides guidance to individuals designing and conducting serosurveys, or studies that test bodily fluids to estimate what part of the population has been vaccinated against or infected with a disease—and how many people remain susceptible. Serosurveys can:
Involve collecting and testing testing blood or oral fluid specimens specimens to measure the amount of antigen-specific antibodies in a group of people,
Reveal what part of the population has been exposed to an infectious disease or been protected from disease by immunizations, and
Estimate the level of population immunity as well as gaps in immunity, such as groups of people who have not been vaccinated or previously exposed.