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A cross-divisional department spanning

The Exposome Collaborative @ Johns Hopkins University

The Exposome Collaborative @ Johns Hopkins University


1. Wild CP. Complementing the genome with an "exposome": the outstanding challenge of environmental exposure measurement in molecular epidemiology. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2005;14(8):1847-50.

2. Wild CP. Environmental exposure measurement in cancer epidemiology. Mutagenesis. 2009;24(2):117-25. PMCID: 2720689.

3. Wild CP. Future research perspectives on environment and health: the requirement for a more expansive concept of translational cancer research. Environmental health : a global access science source. 2011;10 Suppl 1:S15. PMCID: 3073193.

4. Rappaport SM, Smith MT. Epidemiology. Environment and disease risks. Science. 2010;330(6003):460-1. PMCID: 4841276.

5. Wild CP. The exposome: from concept to utility. International journal of epidemiology. 2012;41(1):24-32.

6. van Tongeren M, Cherrie JW. An integrated approach to the exposome. Environmental health perspectives. 2012;120(3):A103-4; author reply A4. PMCID: 3295361.

7. Bouhifd M, Beger R, Flynn T, Guo L, Harris G, Hogberg H, et al. Quality assurance of metabolomics. Altex. 2015;32(4):319-26. PMCID: 5578451.

8. Myint L, Kleensang A, Zhao L, Hartung T, Hansen KD. Joint Bounding of Peaks Across Samples Improves Differential Analysis in Mass Spectrometry-Based Metabolomics. Analytical chemistry. 2017;89(6):3517-23. PMCID: 5362739.

9. Ramirez T, Daneshian M, Kamp H, Bois FY, Clench MR, Coen M, et al. Metabolomics in toxicology and preclinical research. Altex. 2013;30(2):209-25. PMCID: 3821217.

10. Ramirez T, Strigun A, Verlohner A, Huener HA, Peter E, Herold M, et al. Prediction of liver toxicity and mode of action using metabolomics in vitro in HepG2 cells. Archives of toxicology. 2018;92(2):893-906. PMCID: 5818600.

11. Bouhifd M, Andersen ME, Baghdikian C, Boekelheide K, Crofton KM, Fornace AJ, Jr., et al. The human toxome project. Altex. 2015;32(2):112-24. PMCID: 4778566.

12. Bowman CE, Zhao L, Hartung T, Wolfgang MJ. Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series. Molecular and cellular biology. 2016;36(15):2089-104. PMCID: 4946427.

13. Bowman CE, Rodriguez S, Selen Alpergin ES, Acoba MG, Zhao L, Hartung T, et al. The Mammalian Malonyl-CoA Synthetase ACSF3 Is Required for Mitochondrial Protein Malonylation and Metabolic Efficiency. Cell chemical biology. 2017;24(6):673-84 e4. PMCID: 5482780.

14. Elgogary A, Xu Q, Poore B, Alt J, Zimmermann SC, Zhao L, et al. Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America. 2016;113(36):E5328-36. PMCID: 5018752.

15. Head SA, Shi W, Zhao L, Gorshkov K, Pasunooti K, Chen Y, et al. Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 2015;112(52):E7276-85. PMCID: 4703001.

16. Lee J, Choi J, Selen Alpergin ES, Zhao L, Hartung T, Scafidi S, et al. Loss of Hepatic Mitochondrial Long-Chain Fatty Acid Oxidation Confers Resistance to Diet-Induced Obesity and Glucose Intolerance. Cell reports. 2017;20(3):655-67. PMCID: 5546239.

17. Regazzoni LG, Grigoryan H, Ji Z, Chen X, Daniels SI, Huang D, et al. Using lysine adducts of human serum albumin to investigate the disposition of exogenous formaldehyde in human blood. Toxicology letters. 2017;268:26-35. PMCID: 5555303.

18. Daniels SI, Sille FC, Goldbaum A, Yee B, Key EF, Zhang L, et al. Improving power to detect changes in blood miRNA expression by accounting for sources of variability in experimental designs. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2014;23(12):2658-66. PMCID: 4256675.

19. Barazesh JM, Prasse C, Sedlak DL. Electrochemical Transformation of Trace Organic Contaminants in the Presence of Halide and Carbonate Ions. Environmental science & technology. 2016;50(18):10143-52. PMCID: 5032050.

20. Brezina E, Prasse C, Meyer J, Muckter H, Ternes TA. Investigation and risk evaluation of the occurrence of carbamazepine, oxcarbazepine, their human metabolites and transformation products in the urban water cycle. Environmental pollution. 2017;225:261-9.

21. Knopp G, Prasse C, Ternes TA, Cornel P. Elimination of micropollutants and transformation products from a wastewater treatment plant effluent through pilot scale ozonation followed by various activated carbon and biological filters. Water research. 2016;100:580-92.

22. Prasse C, Ford B, Nomura DK, Sedlak DL. Unexpected transformation of dissolved phenols to toxic dicarbonyls by hydroxyl radicals and UV light. Proceedings of the National Academy of Sciences of the United States of America. 2018;115(10):2311-6. PMCID: 5877969.

23. Prasse C, Stalter D, Schulte-Oehlmann U, Oehlmann J, Ternes TA. Spoilt for choice: A critical review on the chemical and biological assessment of current wastewater treatment technologies. Water research. 2015;87:237-70.

24. Prasse C, Wagner M, Schulz R, Ternes TA. Oxidation of the antiviral drug acyclovir and its biodegradation product carboxy-acyclovir with ozone: kinetics and identification of oxidation products. Environmental science & technology. 2012;46(4):2169-78.

25. Schlüter-Vorberg L, Prasse C, Ternes TT, Mückter H, Coors A. Toxification by Transformation in Conventional and Advanced Wastewater Treatment: The Antiviral Drug Acyclovir. Environ Sci Technol Lett. 2015;2(12):342–6.

26. Buck Louis GM, Sundaram R. Exposome: time for transformative research. Statistics in medicine. 2012;31(22):2569-75. PMCID: 3842164.

27. Lioy PJ, Rappaport SM. Exposure science and the exposome: an opportunity for coherence in the environmental health sciences. Environ Health Perspect. 2011;119(11):A466-7. PMCID: 3226514.

28. Betts KS. Characterizing exposomes: tools for measuring personal environmental exposures. Environ Health Perspect. 2012;120(4):A158-63. PMCID: 3339478.

29. Miller GW, Jones DP. The nature of nurture: refining the definition of the exposome. Toxicol Sci. 2014;137(1):1-2. PMCID: 3871934.

30. DeBord DG, Carreon T, Lentz TJ, Middendorf PJ, Hoover MD, Schulte PA. Use of the "Exposome" in the Practice of Epidemiology: A Primer on -Omic Technologies. American journal of epidemiology. 2016;184(4):302-14. PMCID: 5025320.

31. Escher BI, Hackermuller J, Polte T, Scholz S, Aigner A, Altenburger R, et al. From the exposome to mechanistic understanding of chemical-induced adverse effects. Environment international. 2017;99:97-106. PMCID: 6116522.

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